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Rat connectome



Median preoptic nucleus left


Abbreviation
MnPO
Color       
Superior regionsPreoptic nucleus

SynonymsAbbr.Language
Nucleus praeopticus medianusMEPOLat
Median preoptic nucleusMEPOEng
Midline at aterior-dorsal border of teh anterior commissure Eng
Median preoptic nucleusMnPOEng
 POMeEng

SubregionsSide
Median preoptic nucleus medial partleft
Ventral part of the median preoptic nucleusleft
Dorsal median preoptic nucleusleft
Median preoptic nucleus caudal levelleft
Median preoptic nucleus rostral levelleft
Median preoptic nucleus middle levelleft
Median preoptic nucleus dorsal-ventral extentleft
Median preoptic nucleus rostrocaudal extentleft
Median preoptic nucleus posterior aspectleft
Median preoptic nucleus anterior ventral aspectleft
Median preoptic nucleus anterior portionleft

Output to

NameSideAbbr.WeightDetails
Anteroposterior extension of the central gray mesencephalic partipsiCGMap3
Between anterior end of dorsal raphe and posterior ventral tegmental nucleus of the central gray mesencephalic partipsiCGMdrvtg3
Periaqueductal grayipsiPAG2
Dorsolateral periaqueductal grayipsiDLPAG1
Dorsomedial periaqueductal grayipsiDMPAG3
Lateral periaqueductal grayipsiLPAG2
Periaqueductal gray caudal partipsiPAGc-0.5
Periaqueductal gray dorsal partipsiPAGd3
Periaqueductal gray rostral partipsiPAGR-0.5
Periaqueductal gray rostrolateral partipsiPAGRL3
Ventral periaqueductal grayipsiVPAG3
Ventrolateral periaqueductal grayipsiVLPAG2
Ventromedial periaqueductal grayipsiVMPAG3
Central tegmental field lateral partipsiTGACL1
Ventral tegmental area A10ipsiVTA-0.5
Laterodorsal tegmental nucleusipsiLDTg0.5
Pedunculopontine tegmental nucleusipsiPPTg0.5
Barringtons nucleusipsiBar1
Locus coeruleusipsiLC1
Rostromedial pericoerulear regionipsiRMPCR-0.5
Prelocus coeruleus nucleusipsiPLC-0.5
Nucleus subincertusipsiNSI3
Rostroventrolateral reticular nucleusipsiRVL-3
Deep mesencephalic nucleus dorsal partipsiDpMeD1
Pontine reticular nucleusipsiPRN3
Parabrachial nucleusipsiPB-0.5
Lateral parabrachial nucleusipsiLPB-0.5
Lateral parabrachial nucleus dorsal partipsiLPBD3
Lateral parabrachial nucleus lateral partipsiLPBL3
Lateral parabrachial nucleus central lateral partipsiLPBCL3
Parabrachial nucleus central lateral partipsiPBCeL3
Rostral portion of the parabrachial nucleus central lateral partipsiPBCeLR1
Parabrachial nucleus dorsolateral partipsiPBDL3
Caudal external lateral parabrachial areaipsiPBceL-0.5
Parabrachial nucleus external divison rostral part of the lateral partipsiPBeDLR3
Rostral third of the barabrachial nucleus external divison lateral partipsiPBeDLrt-0.5
Parabrachial nucleus medialipsiPBnMe-0.5
Gigantocellular reticular nucleus alpha partipsiGiA0.5
Supratrigeminal nucleusipsiSu53
Mesencephalic trigeminal nucleusipsiMe53
Peritrigeminal zoneipsiP5-0.5
Dorsal raphe nucleusipsiDR-0.5
Dorsal raphe nucleus caudal partipsiDRC1
Dorsal raphe nucleus central partipsiDRcep3
Dorsal raphe nucleus dorsal coreipsiDRDc0.5
Dorsal raphe nucleus lateral wingipsiDRlw1
Dorsal raphe nucleus rostral partipsiDRr1
Dorsal raphe nucleus ventral partipsiDRV0.5
Dorsal raphe nucleus ventrolateral partipsiDRVL0.5
Median raphe nucleusipsiMnR1.5
Midline apneic siteipsiMAS3
Raphe magnus nucleusipsiRMg3
Raphe magnus nucleus caudal partipsiRMgc0.5
Raphe magnus nucleus rostral partipsiRMgR1
Raphe nuclei rostral partipsiRANR-0.5
Raphe pallidus nucleusipsiRPa3
Raphe pallidus nucleus rostral partipsiRParo3
Caudal one-third of the rostral part of the raphe pallidus nucleusipsiCotRParo3
Ventral lateral medulla oblongataipsiMVL-0.5
Median eminenceipsiME0.5
Diagonal band of BrocaipsiDBB0.5
Substantia innominataipsiSI-0.5
Medial tuberal nucleusipsiMTuN3
Lateral preoptic areaipsiLPO0
Medial preoptic areaipsiMPA0.5
Magnocellular preoptic nucleusipsiMCPO-0.5
Medial preoptic nucleusipsiMPO1
Ventrolateral preoptic nucleusipsiVLPO3
Extended ventrolateral preoptic nucleusipsieVLPO2
Core of the ventrolateral preoptic areaipsiVLPOco3
Ventromedial preoptic nucleusipsiVMPO-0.5
Vascular organ of the lamina terminalisipsiVOLT-0.5
Dorsomedial hypothalamic nucleusipsiDMHy3
Juxtaparaventricular part caudal [Lateral hypothalamic area [Preoptic anterior region]]ipsiJPVC0.5
Juxtaparaventricular part rostral [Lateral hypothalamic area [Preoptic anterior region]]ipsiJPVR1
Lateral zoneipsiLHA3
Lateral hypothalamic areaipsiLH4
Lateral hypothalamic area dorsal partipsiLHd-0.5
Lateral hypothalamic area juxtadorsomedial regionipsiJDM3
Lateral hypothalamic area medial partipsiLHAm3
Lateral hypothalamic area motor related juxtaventromedial region dorsal zoneipsiLHAjvd2
Lateral hypothalamic area motor related juxtaventromedial region ventral zoneipsiLHAjvv2
Lateral hypothalamic area perifornical partipsiPFx3
Lateral hypothalamic area [Lateral zone tuberal level]ipsiLHtu0.5
Magnocellular nucleus of the lateral hypothalamusipsiMCLH-2
Medial division of the hypothalamusipsiMdH2
Anterior hypothalamic area posterior partipsiAHAP0.5
Anteroventral periventricular nucleus [Anterior hypothalamic area]ipsiAVPe3
Anteroventral preoptic nucleusipsiAnV1
Dorsal hypothalamic areaipsiDA3
Dorsomedial hypothalamic nucleus [Medial zone]ipsiDM3
Parastriatal nucleusipsiPS1
Subparaventricular zoneipsiSuPZ3
Ventromedial hypothalamic nucleusipsiVMH3
Mediobasal hypothalamus anterior partipsiMeHypoAnt1
Mediobasal hypothalamus posterior partipsiMeHypoP1
Anteroventral periventricular nucleus 2ipsiAVPV20.5
Arcuate nucleusipsiArc3
Nucleus paraventricularis [Periventricular zone anterior region]ipsiPaPAR2
Nucleus paraventricularis parvocellular partipsiPaPaP-0.5
Paraventricular hypothalamic nucleus medial parvicellular part [Periventricular zone anterior region]ipsiPaMP-0.5
Paraventricular hypothalamic nucleus medial parvocellular partipsiMPPa-0.5
Paraventricular hypothalamic nucleus posterior part [Periventricular zone anterior region]ipsiPaPo0.5
Paraventricular hypothalamic nucleusipsiPa4
Mid paraventricular hypothalamic nucleusipsiMiPa-0.5
Paraventricular hypothalamic nucleus magnocellular divisionipsiPaMag2
Paraventricular hypothalamic nucleus caudal part of the magnocellular divisionipsiPaCMag3
Paraventricular hypothalamic nucleus magnocellular division posterior partipsiPaMagP-0.5
Paraventricular hypothalamic nucleus parvocellular divisionipsiPavPo2
Paraventricular nucleus medial parvocellular partipsiPaMep-0.5
Caudal portion of the paraventricular nucleus dorsal part of the medial parvocellular subdivisionipsiPadMepC3
Paraventricular nucleus anterior partipsiPaan0.5
Paraventricular nucleus dorsal edgeipsiPaDoE0.5
Paraventricular nucleus dorsal most portionipsiPaDom0.5
Paraventricular nucleus medial part at mid paraventricular hypothalamic nucleus levelipsiPamemi0.5
Paraventricular nucleus medial part at posterior paraventricular hypothalamic nucleus levelipsiPamepo0.5
Peri-paraventricular hypothalamic nucleusipsiPPa0.5
Periventricular hypothalamic nucleusipsiPe1
Subparaventricular zone of the hypothalamusipsiSPa-0.5
Suprachiasmatic nucleusipsiSCh3
Supraoptic nucleus [Supraoptic region]ipsiSO4
Episupraoptic nucleusipsiESO0
Nucleus properipsiSOnP2
Supraoptic nucleus anterior divisionipsiSOA2
Supraoptic nucleus dorsal partipsiSOd-0.5
Supraoptic nucleus perinuclear zoneipsiSOpnz3
Supraoptic nucleus posterior partipsiSOP2
Supraoptic nucleus tuberal partipsiSOT2
Supraoptic nucleus ventral part [Supraoptic region]ipsiSOV1
Supraoptic nucleus rostral partipsiSOr3
Area immediately surrounding the supraoptic nucleusipsiSOsur1
Premammillary nucleus ventral partipsiPMV1
Perifornical nucleusipsiPeF-0.5
Dorsochiasmatic areaipsiDRCh3
Mediodorsal thalamic nucleusipsiMD3
Mediodorsal thalamic nucleus medial partipsiMDM2
Midline group of the dorsal thalamusipsiMTN2
Paraventricular thalamic nucleusipsiPV3
Reuniens thalamic nucleusipsiRe1
Reuniens thalamic nucleus ventral partipsiReV-0.5
Reuniens thalamic nucleus most ventral partipsiRemV3
Subfornical organipsiSFO3
Zona incertaipsiZI3
Zona incerta medial tipipsiZImt0.5
Optic chiasmipsiox3
Medial habenular nucleusipsiMHb2
Pineal glandipsiPi3
Anterior lobe of pituitaryipsiAPit0
Intermediate lobe of pituitaryipsiIPit0
Posterior lobe of pituitaryipsiPPit1
Rostral part of the posterior lobe of pituitaryipsiPPitr1
Vasopressinergic fiber bundle in the ventromedial stalk and postrior lobeipsiPITvaso1
Bed nucleus of the stria terminalisipsiBST1.5
Ventral hippocampal commissureipsivhc1
Cingulate cortexipsiCg-0.5
Infralimbic cortex deep layersipsiILDL-0.5
Insular cortexipsiICX-0.5
Lateral septal nucleus ventral partipsiLSV2
Triangular septal nucleusipsiTS1
Septohypothalamic nucleusipsiSHy2
Intermediolateral cell columnipsiIML-0.5
Anteroposterior extension of the central gray mesencephalic partcontraCGMap-0.5
Between anterior end of dorsal raphe and posterior ventral tegmental nucleus of the central gray mesencephalic partcontraCGMdrvtg-0.5
Periaqueductal graycontraPAG1
Dorsolateral periaqueductal graycontraDLPAG1
Dorsomedial periaqueductal graycontraDMPAG1
Lateral periaqueductal graycontraLPAG1
Periaqueductal gray dorsal partcontraPAGd1
Ventral periaqueductal graycontraVPAG1
Ventrolateral periaqueductal graycontraVLPAG1
Ventromedial periaqueductal graycontraVMPAG1
Laterodorsal tegmental nucleuscontraLDTg-0.5
Barringtons nucleuscontraBar0.5
Locus coeruleuscontraLC-0.5
Rostromedial pericoerulear regioncontraRMPCR-0.5
Rostroventrolateral reticular nucleuscontraRVL-3
Lateral parabrachial nucleuscontraLPB-0.5
Lateral parabrachial nucleus dorsal partcontraLPBD-0.5
Lateral parabrachial nucleus lateral partcontraLPBL-0.5
Lateral parabrachial nucleus central lateral partcontraLPBCL-0.5
Parabrachial nucleus medialcontraPBnMe-0.5
Midline apneic sitecontraMAS3
Raphe magnus nucleuscontraRMg3
Raphe pallidus nucleuscontraRPa3
Caudal one-third of the rostral part of the raphe pallidus nucleuscontraCotRParo3
Ventral lateral medulla oblongatacontraMVL-0.5
Median eminencecontraME-0.5
Medial preoptic areacontraMPA-0.5
Medial preoptic nucleuscontraMPO0.5
Ventrolateral preoptic nucleuscontraVLPO2
Ventromedial preoptic nucleuscontraVMPO-0.5
Dorsomedial hypothalamic nucleus [Medial zone]contraDM-0.5
Anteroventral periventricular nucleus 2contraAVPV20.5
Paraventricular hypothalamic nucleuscontraPa-0.5
Paraventricular nucleus medial partcontraPame0.5
Supraoptic nucleus anterior divisioncontraSOA-0.5
Sinoatrial nodeipsiSinoAtri1
Stellate ganglionipsiAutoSteG-0.5
Ganglia around the heartipsiAutoGHeart1
Sympathetic nervous systemipsiSNS0
Parasympathetic nervous systemipsiPaNS2
Ventricle muscle wallipsiOrgsCorVenMyo1
Intercapsular brown adipose tissueipsiOrgBATi-10
Sublingual glandipsiOrgSubLGL-0.5
Submandibular glandipsiOrgsSubg-0.5
Femoral bone marrowipsiOrgSkFemM1
KidneyipsiOrgsKid1
Sublingual glandcontraOrgSubLGL-0.5
Submandibular glandcontraOrgsSubg-0.5
KidneycontraOrgsKid-0.5

Input from

NameSideAbbr.WeightDetails
Central gray lateral partipsiCGL0
Periaqueductal grayipsiPAG2.5
Dorsomedial periaqueductal grayipsiDMPAG2.5
Lateral periaqueductal grayipsiLPAG2.5
Periaqueductal gray dorsal partipsiPAGd2.5
Ventrolateral periaqueductal grayipsiVLPAG2.5
Central tegmental field lateral partipsiTGACL0
Ventral tegmental area A10ipsiVTA0
Ventral tegmental area A10 parabrachial divisionipsiVTApb3
Locus coeruleusipsiLC1
Parabrachial nucleusipsiPB3
Koelliker Fuse nucleusipsiKF2.5
Lateral parabrachial nucleusipsiLPB2.5
Lateral parabrachial nucleus external partipsiLPBE2.5
Lateral parabrachial nucleus superior partipsiLPBS1
Parabrachial nucleus central partipsiPBCe2.5
Parabrachial nucleus central lateral partipsiPBCeL-0.5
Parabrachial nucleus dorsal partipsiPBD2.5
Dorsal lateral parabrachial nucleusipsiPBDoL-0.5
Parabrachial nucleus external divisonipsiPBeD2.5
Parabrachial nucleus external divison lateral partipsiPBeDL-0.5
Parabrachial nucleus medialipsiPBnMe3
Medial parabrachial nucleus external partipsiMPBE2.5
Parabrachial nucleus rostral partipsiPBro1
Parabrachial nucleus ventral partipsiPBV2.5
Parabrachial nucleus ventral part medial portionipsiPBVM2.5
Gigantocellular reticular nucleusipsiGi1
C1 adrenaline cellsipsiC1-0.5
Nucleus of the solitary tractipsiSol-0.5
Nucleus of the solitary tract commissural partipsiSolC-0.5
Nucleus of the solitary tract medial partipsiSolM-0.5
Dorsal motor nucleus of vagus dorsolateral edgeipsi10DLe-0.5
Median raphe nucleusipsiMnR0
Pontine raphe nucleusipsiPnR-0.5
Raphe magnus nucleus rostral partipsiRMgR3
Ventral lateral medulla oblongataipsiMVL-0.5
Caudal ventrolateral medullaipsiCVLM3
Rostral ventrolateral medullaipsiRVLM-10
Lateral external cuneate nucleus dorsal partipsiLECUd1
Dorsal paragigantocellular nucleusipsiDPGi1
Diagonal band of BrocaipsiDBB-2
Medial septal nucleus medial partipsiMSm-2
Substantia innominataipsiSI2
Lateral preoptic areaipsiLPO2
Medial preoptic areaipsiMPA3
Medial preoptic area dorsolateral partipsiMPADL2
Medial preoptic nucleusipsiMPO3
Ventrolateral preoptic nucleusipsiVLPO-2
Ventrolateral preoptic nucleus posterior partipsiVLPOP-0.5
Anterior preoptic nucleusipsiPREnA-0.5
Dorsolateral preoptic regionipsiPREOdL-2
Dorsal tuberomammillary nucleusipsiDTM3
Vascular organ of the lamina terminalisipsiVOLT1.5
Dorsomedial hypothalamic nucleusipsiDMHy4
Juxtaparaventricular part caudal [Lateral hypothalamic area [Preoptic anterior region]]ipsiJPVC0.5
Juxtaparaventricular part rostral [Lateral hypothalamic area [Preoptic anterior region]]ipsiJPVR0
Lateral hypothalamic area anterior part [Preoptic anterior region]ipsiLHAapar0
Lateral hypothalamic area posterior part [Preoptic anterior region]ipsiLHApPAR0
Lateral hypothalamic area premammillary subfornical region [Preoptic anterior region]ipsiLHAsfp1
Lateral zoneipsiLHA0
Lateral hypothalamic areaipsiLH2
Lateral hypothalamic area juxtadorsomedial regionipsiJDM1
Lateral hypothalamic area motor related juxtaventromedial regionipsiLHAjvm0
Lateral hypothalamic area motor related juxtaventromedial region dorsal zoneipsiLHAjvd0.5
Lateral hypothalamic area motor related juxtaventromedial region ventral zoneipsiLHAjvv0
Lateral hypothalamic area subfornical region anterior zoneipsiLHAsfa0
Lateral hypothalamic area perifornical partipsiPFx2
Tuberal region of lateral hypothalamusipsiTuLH-0.5
Most anterior part of the parvalbumin-positive nucleus of the lateral hypothalamusipsiPV1ma-0.5
Anterior hypothalamic areaipsiAHA3
Anterior hypothalamic nucleus ventromedial partipsiAHAvm1
Anteroventral periventricular nucleus [Anterior hypothalamic area]ipsiAVPe1
Dorsal hypothalamic areaipsiDA3
Dorsomedial hypothalamic nucleus [Medial zone]ipsiDM2
Dorsomedial hypothalamic nucleus dorsomedial partipsiDMDM2
Dorsomedial hypothalamic nucleus ventral partipsiDMV-0.5
Posterior hypothalamic areaipsiPHA3
Posterior hypothalamic nucleus caudal partipsiPHCa1
Posterior hypothalamic nucleus rostral partipsiPHRo0
Subparaventricular zoneipsiSuPZ3
Lateral part of ventral subparaventricular zoneipsiSuPZvL0.5
Subparaventricular zone ventromedial partipsiSuPZvm3
Subparaventricular zone dorsomedial partipsiSuPZdm0.5
Subparaventricular zone dorsolateral partipsiSuPZdL0.5
Ventromedial hypothalamic nucleusipsiVMH3
Ventromedial hypothalamic nucleus ventrolateral partipsiVMHVL1
Arcuate nucleusipsiArc-0.5
Dorsomedial hypothalamic nucleus [Periventricular zone]ipsiDMpz3
Nucleus paraventricularis [Periventricular zone anterior region]ipsiPaPAR3
Paraventricular hypothalamic nucleus parvicellular part [Periventricular zone anterior region]ipsiPaPc1.5
Paraventricular hypothalamic nucleus medial parvicellular part [Periventricular zone anterior region]ipsiPaMP-0.5
Paraventricular hypothalamic nucleus anterior parvicellular part [Periventricular zone anterior region]ipsiPaAP2
Paraventricular hypothalamic nucleusipsiPa3
Paraventricular hypothalamic nucleus parvocellular divisionipsiPavPo0.5
Paraventricular hypothalamic nucleus dorsal parvocellular divisionipsiPavPoD-0.5
Paraventricular hypothalamic nucleus parvocellular division posterior partipsiPavPoP-0.5
Paraventricular hypothalamic nucleus parvocellular division ventral partipsiPavPoV-0.5
Paraventricular hypothalamic nucleus periventricular partipsiPapv-0.5
Periventricular hypothalamic nucleusipsiPe-0.5
Preoptic periventricular nucleusipsiPePO-0.5
Subparaventricular zone of the hypothalamusipsiSPa2
Subparaventricular zone of the hypothalamus perisuprachiasmatic regionipsiSBPVps3
Suprachiasmatic nucleusipsiSCh0.5
Suprachiasmatic nucleus dorsomedial partipsiSCnDM3
Suprachiasmatic nucleus ventrolateral partipsiSCnVL2
Supraoptic nucleus [Supraoptic region]ipsiSO-0.5
Premammillary nucleus ventral partipsiPMV1.5
Supramammillar nucleusipsiSuM0
Perifornical nucleusipsiPeF2
Retrochiasmatic areaipsiRCh2
Dorsochiasmatic areaipsiDRCh2
Anteromedial thalamic nucleusipsiAM2
Central medial thalamic nucleusipsiCM1
Centrolateral thalamic nucleusipsiCL1
Rhomboid thalamic nucleusipsiRh1
Submedius thalamic nucleusipsiSub1
Paraventricular thalamic nucleus anterior partipsiPVA1.5
Reuniens thalamic nucleusipsiRe3
Subfornical organipsiSFO3
Central core of the subfornical organipsiSFOC3
Peripheral region of the subfornical organipsiSFOP3
Rostral subfornical organipsiSFOR3
Subfornical organ outer rimipsiSFOor3
Subparafascicular thalamic nucleusipsiSPF1
Zona incertaipsiZI0
Anterior basomedial nucleusipsiBMA1
Posterior basomedial nucleusipsiBMP-0.5
Dorsolateral part of the lateral nucleusipsiLaDL1
Bed nucleus of the stria terminalisipsiBST3
Bed nucleus of the stria terminalis anterior division dorsomedial nucleusipsiBSTdm3
Bed nucleus of the stria terminalis anterior lateral areaipsiBSTAL1
Bed nucleus of the stria terminalis anterior ventral areaipsiBSTAV1
Bed nucleus of the stria terminalis magnocellular nucleusipsiBSTmc2
Bed nucleus of the stria terminalis medial divisionipsiBSTM0
Bed nucleus of the stria terminalis ventral tipipsiBNSTvt2
Medial amygdaloid nucleusipsiMe0
Subiculum ventral partipsiSv0.5
Columns of the fornixipsicoLf-2
Infralimbic cortexipsiIL2
Lateral septal nucleusipsiLS3
Lateral septal nucleus ventral partipsiLSV4
Septohypothalamic nucleusipsiSHy4
Locus coeruleuscontraLC1
Parabrachial nucleuscontraPB3
Parabrachial nucleus medialcontraPBnMe3
Parabrachial nucleus rostral partcontraPBro1
Nucleus of the solitary tract commissural partcontraSolC-0.5
Nucleus of the solitary tract medial partcontraSolM-0.5
Pontine raphe nucleuscontraPnR-0.5
Ventral lateral medulla oblongatacontraMVL-0.5
Caudal ventrolateral medullacontraCVLM2
Ventrolateral preoptic nucleus posterior partcontraVLPOP-0.5
Anterior preoptic nucleuscontraPREnA-0.5
Tuberal region of lateral hypothalamuscontraTuLH-0.5
Anteroventral periventricular nucleus [Anterior hypothalamic area]contraAVPe0.5
Anterior hypothalamic nucleuscontraAHn-2
Ventromedial hypothalamic nucleus ventrolateral partcontraVMHVL0.5
Arcuate nucleuscontraArc-0.5
Paraventricular hypothalamic nucleus medial parvicellular part [Periventricular zone anterior region]contraPaMP-0.5
Paraventricular hypothalamic nucleus parvocellular divisioncontraPavPo-0.5
Paraventricular hypothalamic nucleus dorsal parvocellular divisioncontraPavPoD-0.5
Paraventricular hypothalamic nucleus parvocellular division ventral partcontraPavPoV-0.5
Paraventricular hypothalamic nucleus parvocellular division posterior partcontraPavPoP-0.5
Paraventricular hypothalamic nucleus periventricular partcontraPapv-0.5
Preoptic periventricular nucleuscontraPePO-0.5
Central core of the subfornical organcontraSFOC1
Rostral subfornical organcontraSFOR3
Subfornical organ outer rimcontraSFOor3

Key for weights

ValueWeight
-3 unknown
-2 fibers of passage
-1 not clear
-0.5 exists
0 not present
0.5 very light
1 light / sparse
1.5 light / moderate
2 moderate / dense
2.5 moderate / strong
3 strong
4 very strong





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